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Conferences 2007/2008

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The European Conference on Contrast Agent Science

Molecular Imaging, Magnetic Resonance, and Intermodality Contrast Agent Research

11th Bi-Annual Conference

Valencia, Spain • 21-23 May 2008

 
 
Wednesday, 21 May
20:00
 Welcome Drinks and Dinner at the Astoria Hotel.
  
 
Thursday, 22 May
 Opening Ceremony and Morning Session I
Chair: Peter A. Rinck
09:00

Opening Words

Presentation of the European Magnetic Resonance Awards 2008
to Klaes Golman (Basic Sciences) and Luis Martí-Bonmatí (Medical Sciences).
Peter A. Rinck and Robert N. Muller on behalf of the Nominating Committee.

09:20 Recent developments within MRI contrast agents.
Klaes Golman.
Malmö, Sweden.
09:50 Discussion
09:55 Pharmacokinetic modeling of cartilage.
Luis Martí-Bonmatí.
Valencia, Spain.
10:25 Discussion
10:30 Coffee Break
  
 Morning Session II
Chair: To be announced
11:00 Contrast agents - the bottles and the labels.
Tom Erling Dahl-Hansen.
Skanem Oslo AS; Lierskogen, Norway.
11:25 Discussion
11:30 Contrast agent plays the role of tracer: pharmacokinetic modeling for MRI is different than for nuclear medicine.
Xin Li, William D. Rooney, and Charles S. Springer, Jr.
Advanced Imaging Research Center; Oregon Health & Science University; Portland, Oregon, 97239; U.S.A.
11:55 Discussion
  
12:00 Lunch Break at the Astoria Hotel
  
 Afternoon Session I
Chair: To be announced
14:00 Hyperpolarized 13C spectroscopic imaging, a way to look at the Krebs cycle.
Per Åkeson.
MR Department, Clinical Section; Copenhagen University Hospital; DK-2650 Hvidovre; Denmark.
14:25 Discussion
14:30 Dynamic Susceptibility Imaging of Brain Tumors. Dose Response and Modeling Considerations.
Atle Bjørnerud.
Division of Oncology, Dept. of Medical Physics and Interventional Centre; Rikshospitalet University Hospital; NO-0027 Oslo, Norway.
14:55 Discussion
15:00 Synthesis and preclinical evaluation of novel blood pool agents.
Heribert Schmitt-Willich and Bernd Misselwitz.
Bayer Schering Pharma, Diagnostic Imaging, Contrast Media Research.
Berlin, Germany.
15:25 Discussion
15:30 Coffee Break
  
 Afternoon Session II
Chair: To be announced
16:00 Nanologs: A nanotechnology analog of monoclonal antibodies for multimodality imaging and drug delivery.
Erik Wiener.
University of Pittsburgh Cancer Institute MRI Facility, University of Pittsburgh Cancer Institute, Hillman Cancer Center. Pittsburgh, PA; U.S.A.
16:25 Discussion
16:30 Detection of inflammatory lesions of the nervous system by Gadofluorine M-enhanced MRI.
Bernd Misselwitz, Martin Bendszus, and Guido Stoll.
Bayer Schering Pharma, Diagnostic Imaging, Contrast Media Research; Berlin, Germany.
16:55 Discussion
17:00 New general method for the synthesis of hydrophilic nanoparticles for MRI applications.
Fernando Herranz (1,3) , Mª Puerto Morales (2), Alejandro G. Roca (2), Ramón Vilar (3), and Jesús Ruiz-Cabello (1).
(1) Universidad Complutense Madrid, Instituto de Estudios Biofuncionales, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Paseo Juan XXIII nº 1, 28040 Madrid, Spain. (2) Instituto de Ciencia de Materiales de Madrid, CSIC, Cantoblanco 28049, Madrid, Spain. (3) Department of Chemistry, Imperial College London, SW7 2AZ London, Great Britain.
17:25 Discussion
17:30 Adjourn
  
18:30

Sightseeing tour of the old city by foot (refreshments will be served on the way).

20:30 Dinner at El Asador de Aranda (specialty: lamb roasted in a clay oven).
  
 
Friday, 23 May
 Morning Session I
Chair: To be announced
09:00 Gadolinium, from contrast media to dose media.
Géraldine Le Duc.
BioMedical Facility, European Synchrotron Radiation Facility, Grenoble, France.
09:25 Discussion
09:30 Quantitative MR imaging of dendritic cells following magnetovaccination.
Christopher M. Long, Hanneke W.M. van Laarhoven, Paul Antony, Hyam I. Levitsky, and Jeff W.M. Bulte.
Johns Hopkins University, School of Medicine; Dept.of Radiology; Baltimore, MD; U.S.A.
09:55 Discussion
10:00 In vitro characterization of Gd and Eu complexes, suitable bimodal contrast agents for MRI and optical imaging.
Luce Vander Elst, Sophie Laurent, C. Galaup, Robert N. Muller, and C. Picard.
Service de Chimie Générale, Organique et Biomédicale; Laboratoire de RMN et d'Imagerie Moléculaire; Université de Mons-Hainaut; Académie Universitaire Wallonie-Bruxelles; BE-7000 Mons, Belgium.
10:25 Discussion
10:30 Coffee Break
  
 Morning Session II
Chair: To be announced
11:00 Substituted DTTA skeleton: a new lead for the synthesis of high relaxivity MRI contrast agents?
Sara Silvério, Susana Torres, José A. Martins, João P. André,
André F. Martins, Lothar Helm, and Carlos F. G. C. Geraldes.
Department de Bioquímica, Faculdade de Ciências e Tecnologia,
Universidade de Coimbra, P.O. Box 3126, PT-3001-401 Coimbra, Portugal.
11:25 Discussion
11:30 Enzymatically activated PARACEST agents.
Eva Jakab Tóth.
Centre de Biophysique Moléculaire. CNRS. Orléans. France.
11:55 Discussion
  
12:00 Lunch Break at the Astoria Hotel
  
 Afternoon Session I
Chair: To be announced
14:00 Nephrogenic Systemic Fibrosis (NSF) – A short review.
Derek Grant.
GE Healthcare, Nycoveien 2, P.O. Box 4220, Nydalen, NO-0401 Oslo, Norway.
14:15 Discussion
14:30 Effects of Gadolinium agents in normal and nephrectomized rats and the relevance of nephrogenic systemic fibrosis.
Derek Grant, Helge Johnsen, Anne Juelsrud, and Dagfinn Løvhaug.
GE Healthcare, Nycoveien 2, P.O. Box 4220, Nydalen, NO-0401 Oslo, Norway.
14:55 Discussion
15:00 Thermodynamic and kinetic stabilities of non-specific gadolinium chelates to predict the risk of gadolinium release in vivo.
Marc Port, Jean-Marc Idée, Christelle Medina, Caroline Robic, Monique
Sabatou, Marie Christine De Golstein, and Claire Corot.
Guerbet Group, Research Department; FR-95943 Roissy CdG Cedex, France.
15:25 Discussion
15:30 Coffee Break
  
 Afternoon Session II
Chair: Robert N. Muller
16:00 Positive contrast with therapeutic iron nanoparticles at 4.7T
Monica Sigovan, Misara Hamoudeh, Achraf Al Faraj, Hatem Fessi, Emmanuelle Canet-Soulas.
Université Lyon 1, CREATIS-LRMN Laboratory and LAGEP Laboratory, UMR CNRS 5220 and 5007, Lyon, France.
16:25 Discussion
16:30 Calix[4]arenes as versatile building blocks in the design of MRI contrast agents.
Daniel Schuehle, Ulf Hanefeld, Juergen Schatz, and Joop A. Peters.
Delft University of Technology, Biocatalysis and Organic Chemistry, Julianalaan 136; NL-2628 BL Delft; The Netherlands
16:55 Discussion
17:00 Rapid and efficient labeling of colorectal cancer cells with a SPION MR contrast agent by electroporation in the presence of protamine sulphate.
Lijun Wang, Zhigang Wang, Tim Frank, Stuart Brown, and Alfred Cuschieri.
Surgical Technology Group; Department of Surgery and Molecular Oncology; Ninewells Hospital; University of Dundee; GB-Dundee DD1 9SY; Great Britain
17:25 Discussion
17:30 Adjourn
  
18:00

Sightseeing tour of the city by bus focusing upon the modern parts of Valencia, among them the Ciutat de les Arts i les Ciències, the harbor and, from the outside, the Oceanographic Parc. At Mercado Colon we will try the Agua de Valencia.

20:30 Local style dinner at La Pepica. Return to the hotel by bus.
  
  


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